EXCELLENT TRUTHS BRINGING TEARS TO MY OWN EYES @70+.

U GOT ONLY LAST 8 DAYS 2 PRAY FOR MERCY FROM HIM[SWT] FOR ME!

Me & My Father

When I was 4 Yrs Old : My father is THE BEST

When I was 6 Yrs Old : My father seems to know everyone

When I was 10 Yrs Old : My father is excellent but he is short tempered

When I was 12 Yrs Old : My father was nice when I was little

When I was 14 Yrs Old : My father started being too sensitive

When I was 16 Yrs Old : My father can't keep up with modern time

When I was 18 Yrs Old : My father is getting less tolerant as the days pass by

When I was 20 Yrs Old : It is too hard to forgive my father, how could my Mum stand him all these years

When I was 25 Yrs Old : My father seems to be objecting to everything I do

When I was 30 Yrs Old: It's very difficult to be in agreement with my father, I wonder if my Grandfather was troubled by my father when he was a youth

When I was 40 Yrs Old: My father brought me up with a lot of discipline, I must do the same

When I was 45 Yrs Old: I am puzzled, how did my father manage to raise all of us

When I was 50 Yrs Old : It's rather difficult to control my kids, how much did my father suffer for the sake of upbringing and protecting us

When I was 55 Yrs Old: My father was far looking and had wide plans for us, he was gentle and outstanding.

When I became 60 Yrs Old: My father is THE BEST

Note that it took 56 Yrs to complete the cycle and return to the starting point "My father is THE BEST "

Let's be good to our parents before it's too late and pray to God that our own children will treat us even better than the way we treated our parents.....

2011 QAREEME
W/S YOUNGER MAMOON UNCLE!!!
----- Original Message -----
From: MCL FREIGHT
To: Undisclosed-Recipient:;
Sent: Wednesday, August 03, 2011 10:41 AM
Subject: My father is THE BEST....

Waptec Media: lie-presentation-attitude-and-position

Waptec Media: lie-presentation-attitude-and-position

lie-presentation-attitude-and-position

Treatment


 The initial treatment requires performing a "leveling" colostomy in the most distal colon with ganglion cells present. This requires exploration laparatomy with multiple seromuscular biopsies of the colon wall to determine the exact extend of the aganglionosis. The colostomy is placed above the transition zone. Placement of the colostomy in an area of aganglionosis will lead to persistent obstruction
 Once the child has reached an adequate size and age (6-12 months; 20 pounds or more), a formal pull-through procedure is done. Three pull-through procedures are currently in use for treating Hirschsprung's disease. The first of these is the original Swenson procedure, in which the aganglionic rectum is carefully dissected in the pelvis and removed down to the anus. The ganglionic colon is then anastomosed to the anus via a perineal approach. In the Duhamel procedure, dissection outside the rectum is confined to the retrorectal space, and the ganglionic colon is anastomosed posteriorly just
 above the anus. The anterior wall of the ganglionic colon and the posterior wall of the aganglionic rectum are anastomosed, using a stapling device. In Soave's operation, dissection is entirely within the rectum. The rectal mucosa is stripped from the muscular sleeve, and the ganglionic colon is brought through this sleeve and anastomosed to the anus. Complications with all procedures include enterocolitis, constipation and anastomotic stricture, but long-term results with the three procedures are comparable and generally excellent in experienced hands. These three procedures also can be
 adapted for total colonic aganglionosis; the ileum is used for the pull-through or anastomosed to the aganglionic segment of distal colon and rectum to improve absorption.

Greetings

Goodmorning guys

Investigation


 Infants with Hirschsprung's disease usually will fail to pass meconium in the first 24 h of life, although this history is often difficult to obtain. Barium enema may be unreliable in diagnosing Hirschsprung's disease in the newborn infant because the colon is not dilated enough to show a transition zone. In older infants and children, barium enema will show the size difference between the dilated ganglionic colon and the distal constricted aganglionic rectal segment. The barium enema in total colonic aganglionous usually shows a markedly shortened colon.
 Rectal biopsy makes the definitive diagnosis of Hirschsprung's disease. Suction rectal biopsy provides a small piece of mucosa and submucosa without the requirement for anesthesia. Occasionally the suction biopsy is not diagnostic and a full-thickness biopsy is required. The histopathology of Hirschsprung's disease is the absence of ganglion cells in the myenteric plexuses, increased staining of a cholinesterase stain and the presence of hypertrophied nerve bundles. Some surgeons have found the use of rectal manometry helpful, particularly in older children, but it is not as accurate a diagnostic tool as is rectal biopsy. Some centers employ manometry, histochemical studies or special stains for diagnosis. These special studies are only as good as the person performing them and interpreting the results

Clinical features


 The presentation may be much subtle, with constipation and abdominal distention as the chief findings. Symptoms usually begin at birth, frequently with delayed passage of meconium. Any newborn who fails to pass meconium in the first 24-48 hours of life should be evaluated for possible Hirschsprung's disease. In some infants, the presentation is that of complete intestinal obstruction. Others have relatively few symptoms until several weeks of age, when the classic symptom of
 constipation has its onset. Diarrhea is not uncommon but differs from the usual infantile diarrhea in that it is associated with abdominal distension. Occasionally the patient will go many years with mild constipation and diagnosis will be delayed. Occasionally failure to thrive is the initial sign.
 The diagnosis is first suspected based on history and physical examinations (characteristically there is no stool in rectum and abdominal distension is painless).

Pathology


 Hirschsprung's disease (HD) is characterized by lack of enteric ganglion cells, hyperplasia of abnormal nerve fibers and a non-propulsive, non-relaxing segment of bowel. Classically the etiology is attributed to a failure of cranio-caudal migration of parasympathetic neural crest cells to the distal bowel. Hirschsprung's is the congenital absence of parasympathetic innervation of the distal intestine. Aganglionic colon does not permit normal peristalsis to occur. Functional obstruction therefore supervenes, and the infant may present with complete colon obstruction or with a devastating enterocolitis. The colon proximal to the aganglionic segment, in an effort to overcome the partial
 obstruction, becomes distended and its wall markedly thickened because of muscle hypertrophy. A plausible explanation for the failure of relaxation of the bowel involved is a deficiency of enteric inhibitory nerves that mediates the relaxation phase of peristalsis. These nerves are intrinsic to the gut and are classify as non-adrenergic and non-cholinergic. Nitric oxide (NO) has recently been implicated as the neurotransmitter which mediates the relaxation of smooth muscle of the GI tract in HD. It's absence
 in aganglionic bowel might account for the failure of relaxation during peristalsis. Besides, adhesions molecules (absent in aganglionic bowel) during early embryogenesis might restrict the neuro-ectodermal origin involved in the initial contact between nerves and muscle cell (synaptogenesis) suggesting that developmental anomaly of innervated muscle and absent NO causes the spasticity characteristic of HD.

Epidemiology

HD occurs 1 in 1000-1500 live births with a 4:1 male predominance. 96% are term appropriate for gestation age (TAGA), 4% are prematures

Hirschsprung's Disease

IntroductionHirschsprung's disease (HD) is a form of functional intestinal obstruction that results from the absence of ganglion cells in the myenteric plexus of the intestine. The precursors of the ganglion cells are neural crest cells that migrate into the intestine from cephalad to caudad. The process is completed by the twelfth week of embryonic life, but the migration from midtransverse colon to anus takes 4 weeks. This increases the time period of vulnerability for failure of migration and accounts for the fact that most cases of aganglionosis involve the rectum and rectosigmoid. Longer segments of absent ganglion cells also may occur, and total colonic aganglionosis, although rare, is also seen.

Health News

BBC News -Parents 'want child gene tests' -what kind of world are we making. soon parents will start asking for the skin color of there kids

Management and Prevention of Ca prostate

Treatment for prostate cancer may involve active surveillance (monitoring for tumor progress or symptoms), surgery (i.e. radical prostatectomy), radiation therapy including brachytherapy (prostate brachytherapy) and external beam radiation therapy, High-intensity focused ultrasound (HIFU), chemotherapy, oral chemotherapeutic drugs (Temozolomide/TMZ), positron emission tomography, cryosurgery, hormonal therapy, or some combination.
Which option is best depends on the stage of the disease, the Gleason score, and the PSA level. Other important factors are the man's age, his general health, and his feelings about potential treatments and their possible side-effects. Because all treatments can have significant side-effects, such as erectile dysfunction and urinary incontinence, treatment discussions often focus on balancing the goals of therapy with the risks of lifestyle alterations. Prostate cancer patients are strongly recommended to work closely with their urologist and use a combination of the treatment options when managing their prostate cancer

A comprehensive worldwide report Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective compiled by the World Cancer Research Fund and the American Institute for Cancer Research reports a significant relation between lifestyle (including food consumption) and cancer prevention. Other research also supports this finding. Exercise and diet may help prevent prostate cancer to the same extent as medications such as alpha-blockers and 5-alpha-reductase inhibitors. The potential role of diet in preventing prostate cancer hsold be looked into.
CONCLUTION
I hope you don’t mind the medical and English mix up in the article, these was aimed at making the commalemal story to be more interesting for you. Thank god ca prostate is a disease of the old age, the Man most have completed his family size before then. Therefore, it does not really affect the reproduction and hence continuity of man existence is guaranteed.

Diagnosis of prostate ca

The only test that can fully confirm the diagnosis of prostate cancer is a biopsy, the removal of small pieces of the prostate for microscopic examination. However, prior to a biopsy, several other tools may be used to gather more information about the prostate and the urinary tract. Digital rectal examination may allow a doctor to detect prostate abnormalities. Cystoscopy shows the urinary tract from inside the bladder, using a thin, flexible camera tube inserted down the urethra. Transrectal ultrasonography creates a picture of the prostate using sound waves from a probe in the rectum
PSA [prostate specific antigen] can be used as a tumor maker to diagnose ca prosrate except Small cell carcinoma, a type of prostate cancer that cannot be diagnosed using the PSA. Other modalilties for diagnosis should be left for the experts.

Pathophysiology of Prostate ca

When normal cells are damaged beyond repair, they are eliminated by apoptosis. Cancer cells avoid apoptosis and continue to multiply in an unregulated manner.
Prostate cancer is classified as an adenocarcinoma, or glandular cancer, that begins when normal semen-secreting prostate gland cells mutate into cancer cells. The region of prostate gland where the adenocarcinoma is most common is the peripheral zone. Initially, small clumps of cancer cells remain confined to otherwise normal prostate glands, a condition known as carcinoma in situ or prostatic intraepithelial neoplasia (PIN). Although there is no proof that PIN is a cancer precursor, it is closely associated with cancer. Over time, these cancer cells begin to multiply and spread to the surrounding prostate tissue (the stroma) forming a tumor. Eventually, the tumor may grow large enough to invade nearby organs such as the seminal vesicles or the rectum, or the tumor cells may develop the ability to travel in the bloodstream and lymphatic system. Prostate cancer is considered a malignant tumor because it is a mass of cells that can invade other parts of the body. This invasion of other organs is called metastasis. Prostate cancer most commonly metastasizes to the bones, lymph nodes, rectum, and bladder.
The PI3k/Akt signaling cascade works with the transforming growth factor beta/SMAD signaling cascade to ensure prostate cancer cell survival and protection against apoptosis. X-linked inhibitor of apoptosis (XIAP) is hypothesized to promote prostate cancer cell survival and growth and is a target of research because if this inhibitor can be shut down then the apoptosis cascade can carry on its function in preventing cancer cell proliferation.[54] Macrophage inhibitory cytokine-1 (MIC-1) stimulates the focal adhesion kinase (FAK) signaling pathway which leads to prostate cancer cell growth and survival.
The androgen receptor helps prostate cancer cells to survive and is a target for many anti cancer research studies; so far, inhibiting the androgen receptor has only proven to be effective in mouse studies. Prostate specific membrane antigen (PSMA) stimulates the development of prostate cancer by increasing folate levels for the cancer cells to use to survive and grow; PSMA increases available folates for use by hydrolyzing glutamated folates

Causes

Causes
Just like other cancers, the specific causes of prostate cancer remain unknown. A man's risk of developing prostate cancer is related to his age, genetics, race, diet, lifestyle, medications, and other factors.
Age
The primary risk factor is age. Prostate cancer is very uncommon in men younger than 45, but becomes more common with advancing age. The average age at the time of diagnosis is 70. However, many men never know they have prostate cancer. In the United States in 2005, there were an estimated 230,000 new cases of prostate cancer and 30,000 deaths due to prostate cancer. Men with high blood pressure are more likely to develop prostate cancer.
Genetics
Genetic background may contribute to prostate cancer risk, as suggested by associations with race, family, and specific gene variants. In the United States, prostate cancer more commonly affects black men than white or Hispanic men, and is also more deadly in black men. No single gene is responsible for prostate cancer; many different genes have been implicated. Mutations in BRCA1 and BRCA2, important risk factors for ovarian cancer and breast cancer in women, have also been implicated in prostate cancer. Other linked genes include the "prostate cancer gene", HPC1, the androgen receptor, and the vitamin D receptor.
Diet
Evidence from epidemiological studies supports a possible protective role in reducing prostate cancer for dietary Vitamin B6, selenium, vitamin E, lycopene, and soy foods. Lower blood levels of vitamin D may increase the risk of developing prostate cancer. This may be linked to lower exposure to ultraviolet (UV) light, since UV light exposure can increase vitamin D in the body. Studies comparing men who live in areas of the country with high levels of selenium to men in areas with low levels suggest that this mineral protects against prostate cancer. An analysis in 2002 of the Nutritional Prevention of Cancer Trial revealed that the men who took selenium supplements daily were half as likely to be diagnosed with prostate cancer. However, in 2008, the Selenium and Vitamin E Cancer Prevention Trial (SELECT) indicated that neither selenium nor vitamin E, alone or in combination, was effective for the primary prevention of prostate cancer. Green tea may be protective (due to its polyphenol content), although the most comprehensive clinical study indicates that it has no protective effect.
Research published in the Journal of the National Cancer Institute suggests that taking multivitamins more than seven times a week can increase the risks of contracting the disease. This research was unable to highlight the exact vitamins responsible for this increase (almost double), although they suggest that vitamin A, vitamin E and beta-carotene may lie at its heart. It is advised that those taking multivitamins never exceed the stated daily dose on the label.
Medication exposure
There are also some links between prostate cancer and medications, medical procedures, and medical conditions. Daily use of anti-inflammatory medicines such as aspirin, ibuprofen, or naproxen may decrease prostate cancer risk. Use of the cholesterol-lowering drugs known as the statins may also decrease prostate cancer risk. Infection or inflammation of the prostate (prostatitis) may increase the chance for prostate cancer. In particular, infection with the sexually transmitted infections chlamydia, gonorrhea, or syphilis seems to increase risk. Finally, obesity and elevated blood levels of testosterone may increase the risk for prostate cancer.
Potential viral cause
In 2006, researchers associated a previously unknown retrovirus, Xenotropic MuLV-related virus or XMRV, with human prostate tumors. Subsequent reports on the virus have been contradictory. A group of US researchers found XMRV protein expression in human prostate tumors, while German scientists failed to find XMRV-specific antibodies or XMRV-specific nucleic acid sequences in prostate cancer samples
to be continued....

COMMALEMAL, Ca Prostate contd

Signs and symptoms
Early prostate cancer usually causes no symptoms. Often it is diagnosed during the workup for an elevated PSA noticed during a routine checkup. It's highly advised to avoid sexual intercourse for 3 days prior to a PSA test because that affects the outcome of the test. Sometimes, however, prostate cancer does cause symptoms, often similar to those of diseases such as benign prostatic hyperplasia. These include frequent urination, increased urination at night, difficulty starting and maintaining a steady stream of urine, blood in the urine, and painful urination. Prostate cancer is associated with urinary dysfunction as the prostate gland surrounds the prostatic urethra. Changes within the gland, therefore, directly affect urinary function. Because the vas deferens deposits seminal fluid into the prostatic urethra, and secretions from the prostate gland itself are included in semen content, prostate cancer may also cause problems with sexual function and performance, such as difficulty achieving erection or painful ejaculation.
Advanced prostate cancer can spread to other parts of the body, possibly causing additional symptoms. The most common symptom is bone pain, often in the vertebrae (bones of the spine), pelvis, or ribs. Spread of cancer into other bones such as the femur is usually to the proximal part of the bone. Prostate cancer in the spine can also compress the spinal cord, causing leg weakness and urinary and fecal incontinence
to be contd....

Cannabis use 'raises psychosis risk' - study

Using cannabis as a teenager or young adult increases the risk of psychosis, a report suggests.

The study published in the British Medical Journal involved tracking 1,900 people over a period of 10 years.

Although the link between cannabis and psychosis is well-established, it had been unclear whether cannabis triggers the disorder.

This research strongly suggests that cannabis use comes first, rather than people taking it for their symptoms.

The research was led by Professor Jim van Os from Maastricht University in the Netherlands, and included researchers from the Netherlands, Germany, Switzerland and the UK.

They excluded anyone who reported cannabis use or pre-existing psychotic symptoms at the start of the study, which took place in Germany.

The participants in the study, aged between 14 and 24, were assessed for cannabis use and psychotic symptoms at three points over a 10-year period.

It found that cannabis use "significantly" increased the risk of psychotic symptoms, even when other factors such as socio-economic status, use of different drugs and other psychiatric conditions were taken into account. for more info., contact BBC news

COMMALEMAL

COMMALEMAL, Ca Prostate
Introduction
The proliferation of literature about the molecular basis of carcinoma has far outpaced the growth of even the most malignant form of cancer yet it is still very important for us to talk about tumors. Cancers use to be a mysterious disease of the white Man, just like development, it will first take origin from the Caucasians before the story now become borderless one. This is probably because it was not diagnosed early enough, or because of environmental and genetic difference or the reason for these is also yet to be understood. Before I continue with the assumption that my readers know what is that cancer, I will like to attempt to remixed the definition of what is these cancer so that those outside the professor will understand. Cancer is that abnormal growth whish is purposeless purposelessness, directionless directionlessness and it can also be seen as being consciousness consciouslessness that is so autonomous to that extend that it dose not obey the command of the normal growth regulators in the bodies of the victims. Because of the above characteristics, cancer cells can invade normal tissues, can spread through the blood and lymphatic thereby causing problems. The body react to the presence of these abnormal cells also add to the problems. When these occur in secretary tissues, the cause over or under secretion of the substance thereby adding to the problem. Because the are autonomy, they consume most of the nutrients in the body to the detriment of the normal tissues. Cancer is not just one disease, there are many types of cancer, almost every tissue in the body can go cancerous.

Cancer don’t have regards to the age, sex, race and social status of the victim. Though Some cancer can occur in women not in men because of the different In body structure that exist in men and women, some occur more in white or in black or more in children, the elderly or the rich. All it need is the right combination of genetic and environmental interplay for it to occur. These article will focus on the most common malignancy I males. It is non other than COMMALEMAL ie Commonest Male Malignancy

to be continued...............

cloning

how will you feel to have a clone of yourself

The Internet and medicine: past, present, and future. D. J. Doyle, K. J. Ruskin, and T. P. Engel Department of Anaesthesia, Toronto Hospital, University of Toronto, Ontario. D. J. Doyle: djdoyle@inforamp.net

Abstract
The enormous growth of the Internet and the World Wide Web has made these two technologies an important potential adjunct to cost-effective health care research and delivery. This article surveys some recent developments in telecommunications, networking and artificial intelligence that are likely to have a significant impact on improving the efficiency and quality of future health care. Issues discussed include: clinical record keeping on the Internet, Internet-assisted medical diagnosis, privacy and security matters, financial transactions, digital money, bandwidth concerns, multimedia (music, audio and video) information delivery via the Internet, intellectual property, and the concept of Information Philanthropy

Internet & Medicine 2.0

Check out this SlideShare Presentation:

Internet & Medicine 2.0

View more presentations from Anuj Sharma.

Internet & Medicine 2.0

Check out this SlideShare Presentation:

Internet & Medicine 2.0

View more presentations from Anuj Sharma.

general info

World Congress on the Internet in Medicine, is an international meeting which aims to bring together researchers, developers and users involved in the application of the Internet in Medicine. The Congress, which will provide a forum for the exploration of the rapidly developing relationship between medical sciences and the Internet, is relevant to all medical and health care professionals, as well as those involved in the development and application of the new technological opportunities offered to the medical field by the Internet and through the use of the World Wide Web. these is an example of what waptec media is out to do. May God help us.

The future of Internet-based medicine is to tie together many different entities: clinical services such as reference laboratories, offices, and hospitals, as well as administrative services such as pharmacies and health plans

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